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Understanding GLP-1 and Its Role in Weight Management GLP-1 is a naturally occurring hormone produced in the intestines in response to food intake

Specific Populations Patients with Renal Impairment An approximately 2-fold increase in the plasma AUC of sitagliptin was observed in patients with moderate renal impairment with eGFR of 30 to less than 45 mL/min/1.73 m2, and an approximately 4-fold increase was observed in patients with severe renal impairment, including patients with ESRD on hemodialysis, as compared to normal healthy control subjects

People with existing depression, anxiety, or other mental health conditions should discuss monitoring plans before starting treatment

Referral to endocrinology for complex cases or to registered dietitians for personalized nutrition guidance can enhance outcomes and provide additional support for patients struggling with weight management despite optimized thyroid treatment

Often, making small changes to your nutrition can be enough to reignite fat loss