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Notably, these neurotoxic effects are rarely seen at doses below 100 mg/day in adults

Nature 414, 782787

Add your chosen diluent, typically bacteriostatic water or sterile water, by directing the stream down the inner wall of the vial

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[14] In patients with diabetes, overly aggressive glycemic control or inadequate adjustment of concurrent diabetes medications (particularly insulin or sulfonylureas) may result in hypoglycemia or relative hypoglycemia, even if glucose values remain within normal range