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Original author: TropicalFishEnglishChina Food & Drug Administration Magazine Minglish Zhujiangshuichang Source: WeChat Public Platform

In the early stages of T2DM, insulin demand increases due to peripheral insulin resistance, when the body compensates by stimulating islet cells to release more insulin, thereby maintaining blood glucose stability

Together, these observations indicated that GLP-1 may have protective effects on beta cells, and raised hopes for long lasting and perhaps disease modifying effects of GLP-1 in diabetes therapy

As estrogen and androgen levels decrease, the HPO axis returns toward typical patterns

While some appreciate the ease, others report no effect and frequent issues with shipping or support