GLP-1 Safety Check
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In support to this theory, it has been demonstrated that GIP infusion increases the proliferation of neuronal progenitors in the dentate gyrus, while mice lacking GIP displayed deterioration in memorial tasks as a result of reduced neurogenesis [24]
[Article] [PubMed] [PMC]11
In the future, large-scale clinical trials should be conducted to further clarify the molecular targets and specific pathways of GLP-1RAs
Ma YL, Kong CY, Guo Z, Wang MY, Wang P, Liu FY, et al
injected low-dose liraglutide and exendin-4 were also attenuated by subdiaphragmatic vagal deafferentation [687,691], but longer-term effects of these compounds on food intake did not depend on intact vagal afferents [691]
