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These side effects may be more intense when starting the medication or when doses are raised

Jastreboff, MD, PhD, a physician-scientist and founding director of the Yale Obesity Research Center

Referral to a Specialist: In some cases, you may be referred to a dermatologist, a doctor who specializes in skin conditions

Possible experiences: strong appetite regulation, 8 to 12 pounds cumulative weight loss, noticeable clothing fit changes, may experience more pronounced GI effects at this increase

Retatrutide has no MHRA or EMA marketing authorisation, and obtaining or using it outside an MHRA-authorised clinical trial is inappropriate and may be unlawful in the UK