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Tirzepatide deprioritization: Many platforms have either discontinued compounded tirzepatide offerings entirely or restricted them to genuine medical necessity cases

That same year, GLP-1 drugs for weight loss represented over 10% of all annual claims among employer-provided plans in the U.S
10.1007/s40200-021-00899-9 36 ParadiesG.ParadiesV.RuggieroF

The difference from previous generations is fundamental: whereas existing drugs target one or two receptors, retatrutide combines three complementary mechanisms in a single molecule