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In lymphedema, impaired contractile/pumping function of lymphatic vessels is a known key determinant in the development and progression of the disease, the observations hereby presented, supported by clinical reports, suggest the therapeutic potential of GLP-1R agonists to directly restore the pumping capacity of collecting lymphatic vessels in secondary lymphedema

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21 The Elixhauser Index categorizes comorbidities using ICD codes and is widely used for risk adjustment in health services research

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