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So when the obesity process starts from energy surplus, all these systems are connected and feeding each other and it puts you in a really bad, vicious cycle and it only gets worse

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*Correspondence: Yue Chen, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers