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In the same study, semaglutide decreased heart failure and all-cause mortality by 18% and 19% (respectively)
Activation of the renin-angiotensin system is an important homeostatic mechanism in states associated with volume depletion, and the use of inhibitors of these systems contributes to occurrence of acute kidney injury in subjects with volume depletion [149]

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Glucagon-Like Peptide-1 Receptor Agonists and Risk for Depression in Older Adults With Type 2 Diabetes: A Target Trial Emulation Study
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