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Although dedicated trials of GLP-1RAs in AITD are lacking, preliminary reports suggest potential impacton thyroid volume, thyroid function, and autoimmune activity

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The incretin hormone, glucagon-like peptide-1 (GLP-1), appears to be involved in both peripheral and central pathways mediating satiation

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Out-of-pocket costs, insurance coverage, side effects and a lack of long-term safety data can be barriers to medication for childhood obesity.