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Description
In the presence of a mixture of gabazine (20 M) and tetrodotoxin (1 M), application GLP-1 significantly increased frequency, but not amplitude of miniature EPSCs via PKA signaling pathway

There are calls for urgent investigation into its impact on mental health, but GPs are urging caution when interpreting the research.

Results In the intention-to-treat analysis, dementia risk was not different between GLP1-RA and DPP4i initiators (hazard ratio [HR] 0.95, 95% confidence interval [CI] 0.871.04
Further research is warranted to investigate the potential roles of weight loss, TSH fluctuations, and levothyroxine dose adjustment after GLP-1RA in mediating the cardiovascular risk.

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