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The MHRA approval was supported by results from Novo Nordisk's OASIS clinical trial programme, which evaluated oral semaglutide in adults living with obesity or overweight with weight-related health conditions
Patterson et al ., 2011b)
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References: 1 Drucker, DJ., et al
SGLT2 inhibition reduces glucose reabsorption at the level of the proximal renal tubule, promotes urinary glucose excretion independent of insulin action, and causes a negative caloric balance ( Figure 1 )
