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Inhibition of GPR43/GPR109a expression by RNA interference Human G-protein-coupled receptor 43 (GPR43) or GPR109a siRNA or negative control (NC) siRNA was mixed with the Lipofectamine 2000 transfection reagent (Invitrogen, California, USA) (Table S1)

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Primary and Secondary Outcomes Authors used national Swedish electronic health registers to identify people with diagnosed depression or anxiety who used antidiabetic medication between 20092022