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Physiology of incretins (GIP and GLP-1) and abnormalities in type 2 diabetes

Furthermore, due to huge global demand, in combination with limitations in the production capacity, there has been a global shortage of GLP-1 RAs throughout 2023 affecting the availability of semaglutide (Ozempic) and liraglutide (Victoza) in particular

Dual- and triple-receptor agonists acting via different receptors and postreceptor pathways seem attractive in view of potentially additive or synergistic effects in the treatment of T2D and obesity

They are entering a period of significant physical, emotional, and social change