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Therefore, amidst the COVID pandemic, the opioid crisis is still raging

Research Insight: The SURMOUNT-5 trial, a phase 3b study, demonstrated that participants treated with tirzepatide experienced a superior percentage change in body weight and waist circumference compared to those treated with semaglutide over 72 weeks

Semaglutide alone may not be enough to lose weight without lifestyle changes
The most common side effects are stomach-related: nausea, diarrhea, vomiting, and constipation, especially during dose escalation

Bypass may also be considered for patients who need revision surgery after prior weight loss procedures
