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44 More promising evidence is available regarding GLP-1 RAs in obesity-related HFpEF

It prompts the pancreas to release insulin when blood sugar is high, suppresses glucagon, and slows digestion actions that work together to lower blood sugar while reducing the risk of hypoglycemia

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In clinical studies, GLP-1 receptor agonists have been associated with modest reductions in LDL cholesterol and total cholesterol, with more variable effects on triglycerides depending on the specific agent and study population