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[8] [9] Comorbidities and concomitant medicines : Patients with type 2 diabetes particularly those taking insulin or sulfonylureas should discuss timing with their clinical team, as reduced appetite following injection may increase the risk of hypoglycaemia and may require dose adjustment of those medicines

Research and clinical trials established that the Ozempic may also induce fatigue in about 11 percent of the patients

Hammond, T

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In addition, macrophages are capable of producing a variety of inflammatory factors, such as NF-B, TNF-, IL-2, IL-6 and IL-8 and activating nuclear transcription factors like NF-B, which also play an important role in the progression of MASLD (92)