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(medically reviewed) FDA Zepbound (tirzepatide) prescribing information Lilly Cares Foundation Patient Assistance Program for Eli Lilly medications Important regulatory update On March 19, 2025, the FDA ended enforcement discretion for compounded tirzepatide

Key lessons: Continuity matters: Early discontinuation correlates with substantially lower weight loss and loss of blood sugar gains

Most researchers who plan to reach the 12mg maintenance dose reconstitute with 2mL instead, which brings the injection volume down to a more manageable range

Magnesium glycinate and magnesium malate are gentler on the digestive system than magnesium oxide, which may worsen loose stools

GLP-1RAs have been widely used for the treatment of T2DM (17)