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The remaining 54.1% [95% CI 29.079.3%] of the effect of tirzepatide on UACR appeared to be direct effects of the pooled tirzepatide doses, with unmodeled variables potentially contributing to some extent [96]

N Engl J Med (2013) 368:40715

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Zepbound highlights the importance of understanding the unique properties of each medication, including their active ingredients and weight loss efficacy, to make informed treatment choices for type 2 diabetes and obesity management

In the SURPASS trials, weight loss was generally in the single-digit percentage range