glp 1 agonist and heart failure JCI Treatment of High-Risk Patients with

While current limited evidence does not suggest these medications directly worsen Crohn's disease activity, their gastrointestinal effects require thoughtful management

75 DayJWOttawayNPattersonJTGelfanovVSmileyDGiddaJet al

(PubMed) Side Effect Profile GI effects (nausea, vomiting, diarrhea/constipation) Similar GI-class effects are commonly reported (especially during dose escalation phases in medical use contexts)

Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine

12 A major limitation of prior studies of GLP-1 RAs in patients with T2D is that they did not specifically assess for sight-threatening complications from DR, which account for most of the long-term ocular morbidity associated with T2D