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doi: 10.1093/gerona/glu073 257 GuoMMiJJiangQ-MXuJ-MTangY-YTianGet al

You can read the abstract of this article at In the SURPASS-4 trial, the dual GIP and GLP-1 receptor agonist tirzepatide demonstrated superior reductions in HbA1c concentrations, bodyweight, and blood pressure compared to titrated daily insulin glargine in individuals with type 2 diabetes and cardiovascular risk

In clinical trials, participants reported an average weight loss of approximately 15% of their body weight over a 72-week period

-11.7 lbs
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This challenge could be overcome by engineer an in vivo reservoir of biologic through a single genome editing treatment