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GLP-1 receptor agonists were not developed to treat autoimmune diseases, though emerging research has identified potential anti-inflammatory mechanisms in some autoimmune conditions

The Chinese government has included the NMPA-approved GLP-1 receptor agonists in the national medical insurance policy to increase the accessibility and affordability of such drugs

Zepbound does not necessarily make ibuprofen less effective, but it does change how quickly it is absorbed

Some patients experience modest appetite adaptation after 36 months on semaglutide, though most maintain strong appetite suppression

However, like semaglutide, tirzepatide is expensive and often difficult to obtain due to shortages and insurance restrictions