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Appetite changes within days to weeks
Here's the difference

Neuroimaging research in obesity populations indicates these medications reduce activation in brain regions associated with food reward and craving (Ten Kulve et al., 2016), potentially addressing the compulsive nature of binge eating

Suddenly they seem, (with some notable provisos see below), like a real possibility

Peer review Peer review information Nature thanks Darleen Sandoval and the other, anonymous, reviewer(s) for their contributions to the peer review of this work
