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A recent publication from JAMA on the analysis of people who have been taking GLP-1 agonists from 2006 to 2020 shows that people who are taking GLP-1 agonists have a nine-fold higher risk of developing acute pancreatitis compared with the older drug for weight loss, bupropion, and four times more frequent intestinal obstruction and three times more frequent gastroparesis

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GLP-1 is an incretin hormone that regulates blood glucose by stimulating insulin secretion, suppressing glucagon, and slowing gastric emptying

These symptoms are often related to hypoglycemia, dehydration, or both