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doi: 10.1016/j.bbrc.2013.06.035 32 ShirakiAOyamaJKomodaHAsakaMKomatsuASakumaMet al

Appetite and Cravings Begin to Shift: Many people feel fuller sooner and have fewer cravings within the first couple of weeks

SGLT-2 Inhibitors (e.g., canagliflozin, dapagliflozin): These medications help eliminate glucose through urine, offering a viable alternative for those who cannot tolerate GLP-1 receptor agonists

This anti-autophagic effect of GLP-1 on endothelial cells at an early stage may be crucial for preventing arteriosclerosis which will further lead to serious cardiovascular complications