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More serious but rare risks include pancreatitis, gallbladder disease, and potential thyroid concerns (based on animal studies with GLP-1 receptor agonists)

If the format holds, it would enable tissue targeting (liver-selective glucagon action, for example) that a free peptide cannot achieve

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Andreozzi F, Raciti GA, Nigro C, Mannino GC, Procopio T, Davalli AM, et al

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