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When ibuprofen is necessary , several strategies can minimise risks: Take with food reduces direct gastric irritation, though Wegovy slows digestion Use the lowest effective dose typically 200-400mg for mild to moderate pain Limit duration avoid prolonged courses without medical supervision Stay well-hydrated particularly important given Wegovy's gastrointestinal effects Consider gastric protection proton pump inhibitors (PPIs) may be appropriate for extended NSAID use if recommended by a clinician based on your risk factors For over-the-counter use, ibuprofen should typically not exceed 1.2g per day (e.g., 400mg three times daily) unless advised by a healthcare professional

Monitoring symptoms, managing lifestyle triggers, and seeking timely medical advice are key

Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): a randomised, open-label, phase 3, non-inferiority trial

Lifestyle modifications: Maintain the progress you've made through healthy eating, regular movement, stress management, and quality sleep