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Patients with certain FTO variants may have naturally higher hunger signals, making them more dependent on GLP-1 therapy and more prone to weight regain if medication response diminishes

In the treatment of diabetes mellitus, its dual actions help lower high blood sugar levels and manage blood pressure

Discussion In this database study, treatment with semaglutide (against sitagliptin, a placebo proxy) led to a reduced risk of MACE, and tirzepatide (against dulaglutide) demonstrated a similar risk reduction in patients at elevated cardiovascular risk with obesity and type 2 diabetes

The starting dose for all new patients is 2.5mg of Mounjaro

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