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Both hepatic endothelial and T cells express the GLP-1R (29), suggesting that GLP-1 medicines may also act locally in the liver to reduce inflammation

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According to FDA labeling, tirzepatide can be stored at temperatures not exceeding 86F (30C) for up to 21 days, but exposure to higher temperatures or for longer periods may affect the medication's stability

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Some insurance companies list GLP-1 medications used for weight loss as a coverage exclusion, which means that even if a patient meets FDA-approved criteria and would benefit from using the medication, the plan will not pay for the medication, she says