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Often, its mistaken for just needing more sleep. In reality, your body is adjusting to a powerful metabolic change

Pricing Disclaimer: All pricing and availability information reflects company disclosures at the time of publication (January 2026) and is subject to change without notice

Risks: Increased heart rate, potential worsening of heart failure with reduced ejection fraction, and rare complications like hypoglycemia or retinopathy

The risks of diarrhea was significantly higher for JNJ-64565111, Exenatide, Liraglutide, Orforglipron and Tirzepatide than for placebo, with Orforglipron having an RR of 5.56