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The difference was that people in the control group started taking a different Type 2 diabetes drug called a DPP-4 inhibitor after their cancer diagnosis

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As subjects were included when either treatment combination was initiated, any previous use of metformin, GLP-1 RA or DPP-4is alone or in combination with any other glucose-lowering drug was allowed

This clinical trial did not include patients with T2D, and the emerging data suggests that the weight-loss effects of tirzepatide are reduced in patients with diabetes, a difference also observed in trials with 2.4 mg of semaglutide 2