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Description

(Worn off into a trillion microscopic flecks, giving us cancer and colitis.) The seduction of transformation is still with us, though, as the prestige of subjugating nature has not faded

After stopping a GLP-1 medication, its effects on gut motility gradually diminish as the drug leaves the system

Albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, orforglipron and semaglutide used in the clinic are monoGLP-1RAs, tirzepatide acts not only on GLP1R, but also on glucose-dependent receptors of insulinotropic peptide (GIP), and retatrutide is a triple agonist of GLP-1, GIP and glucagon receptors

Widespread use (75%) of GLP-1 RAs in the total population with type 2 diabetes was projected to prevent 16,455 MIs, 20,409 strokes, 37,100 HF hospitalisations and 39,917 deaths, but increase the number of ESKD events by 170