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Despite some conflicting results obtained in knockout animals, it is clear that the H3R plays an important role in regulating food intake, and its activation is generally orexigenic

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The -Hydroxybutyrate-GPR109A Receptor Regulates Fasting-induced Plasticity in the Mouse Adrenal Medulla

Another important finding of our study was that the inhibitory effect of OB GLP-1 signalling on the SNS was dependent on a GABAergic relay in the PVN
