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New Zealand | In depth: The people who were first in line might not be the people who urgently need it Researchers noticed in diabetes trials that patients on semaglutide were losing significant amounts of weight, so Novo Nordisk, the company that owns Ozempic, began testing the drug for indications of weight loss specifically

Another notable candidate in Eli Lilly obesity pipeline is retatrutide , a triple-hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors

As of mid-2025, retatrutide remains in clinical trials and has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

If you want to understand what meaningful progress actually looks like beyond the scale, our post on the benefits of strength training covers what changes in your body, your energy, and your daily life when you train consistently

Clinical trials show comparable weight loss outcomes across all approved injection sites (abdomen, thigh, upper arm) when patients follow the same dosing schedule and maintain proper injection technique