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Furthermore, GLP-1 has the ability to decrease gastric acid secretion and postprandial gastric emptying, limit gastric and duodenal peristalsis through vagus nerve inhibition, and raise pylorus pressure, all of which contribute to a decrease in appetite, weight loss, and the so-called "ileal braking" effect [121]

The protein kinase RNA-like ER kinase (PERK) is a receptor for TMAO

Their anti-inflammatory and immunomodulatory properties may make them the first real disease-modifying therapy for osteoarthritis

Sudden weight loss (Type 1 diabetes)

Monthly follow-ups (15-20 min): Titrate dose, manage side effects, provide behavioral support, track progress
