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PubMed Central , doi:10.4239/wjd.v13.i3.129

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[1] The development of these two classes of drugs was based upon observations from the early twentieth century when it was noted that factors secreted from the gut participated in the regulation of pancreatic endocrine secretion

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Prohibited medications usually include those that could harm a recipient, such as certain blood thinners, acne medications like Accutane, or drugs used to treat hair loss