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With HCG, studies do not show any real benefit beyond what would happen from following the very low-calorie diet alone

We excluded review articles, case reports, case series, non-randomized controlled trials, systematic reviews, letters to editors, abstracts, and publication in languages other than English

For a deeper look at that process, our article on how GLP-1 actually works for weight loss breaks down the appetite and digestion effects in more detail

This combination therapy targets multiple aspects of glucose regulation, making it a more thorough approach