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Current evidence suggests sequential or alternative approaches may be safer

Over 30 million Americans are using medications like Wegovy and Ozempic, but surgeons say rapid muscle loss is causing an unexpected side effect: back pain.

However, no retrospective epidemiological studies can provide definitive answers, and nausea, vomiting and diarrhoea remain the most clinically relevant adverse effects of these drugs, compromising long-term adherence.

Known generically as semaglutide, Ozempic works by mimicking a hormone that regulates appetite and food intake, leading many patients to experience notable weight reduction

A Kaiser Family Foundation study revealed about one in eight adults in the US say theyre taking a GLP-1 drug such as Ozempic, Wegovy or Zepbound.