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Boyer 2016): Mild to Moderate symptoms: removal of causative agents symptoms may persist in patients taking drugs with long elimination half-lives or active metabolites supportive care i.v

Many patients start with the more affordable semaglutide option and later switch to tirzepatide for more aggressive weight loss

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If this happens, try injecting earlier in the evening, around 6 PM to 7 PM, to push the peak nausea window earlier

In brief, in SURMOUNT-1, participants were randomized 1:1:1:1 to once-weekly, subcutaneous tirzepatide (5, 10, or 15 mg) or placebo for 72 weeks, followed by a 4-week safety follow-up period without treatment