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Description
Not necessarily as a routine starting point, but its reasonable in certain contexts

Because retatrutide includes GLP-1 agonism (which semaglutide was providing) plus GIP and glucagon agonism, the transition should not result in loss of appetite suppression during the switch

[DOI] [PubMed] [Google Scholar] Song DH, Getty-Kaushik L, Tseng E, Simon J, Corkey BE, Wolfe MM

Muskiet, M

So far, this is an anecdotal phenomenon
