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Reusing needles increases the risk of infection and makes the injection more painful

This may help explain why GLP-1 drugs are so effective in helping some people with obesity lose weight

18 This was observed in the early study by Herse and Hooker, 5 and also reported from three other prospective studies, 19-21 while a conclusion of no measurable difference in the induced was provided in two other study reports

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Also, using in silico approaches, pathogenic variants of the GLP1R gene that may impact receptor function and correlate to obesity and diabetes phenotypes have been identified 40