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For composite kidney outcomes, the HR was 0.52 (95% CI 0.330.83) with SGLT2is and 0.70 (95% CI 0.590.83) without SGLT2is ( P -value for interaction 0.38) (Table 3)
Furthermore, NaB promoted GLP-1-mediated upregulated IRS-1 expression and phosphorylation of AMPK and ACC (Fig
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