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2022a, b, c
This beneficial remodeling often outweighs any initial rate elevation
The dose is then increased at 4-week intervals through the 0.5 mg, 1 mg, and 1.7 mg strengths until the maintenance dose of 2.4 mg is reached
23 The SURMOUNT-1 trial revealed a mean percent change in BW over placebo of 15%, 19.5% and 20.9% in those receiving tirzepatide at doses of 5, 10, and 15 mg, respectively
