can tirzepatide cause indigestion vs. Gastroparesis Side Effects: What to Know can tirzepatide cause gerd Does

Semaglutide and Tirzepatide are both GLP-1 receptor agonists, with Tirzepatide having additional action on and a higher affinity for glucose-dependent insulinotropic polypeptide (GIP) receptors

doi:10.1186/1471-2202-13-33 11

These smaller losses may not seem as dramatic

Another 167 patients (17%) withdrew from the trial during the run-in period with approximately one-half of these patients doing so because of gastrointestinal adverse reactions [see Adverse Reactions (6.1)]

The structural similarity between ERR and estrogen receptor DNA-binding domains raises theoretical questions about potential crosstalk, though SLU-PP-332 has been shown to be selective for ERRs over ERs in biochemical assays