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What is next in the Evolution of GLP-1-based Therapies for Diabetes and Obesity

So when it falls, we're gonna see reduced glucose being pooled out of the bloodstream, increased liver output of glucose and adrift towards insulin resistance

In the class labeling these are treated as prompts to halt and obtain evaluation, not symptoms to push through

2023, Harvard Health Publishing

Cocaine Only limited clinical evidence is available for GLP-1RAs in cocaine misuse: a small ( N = 13) proof-of-concept trial across 2 days showed that exenatide compared with placebo did not reduce the number of self-administered cocaine infusions 115 , while a case series of 3 individuals with cocaine-use disorder highlighted the feasibility and safety of using the same drug over 6 weeks, although no efficacy measures were reported 116