glp 1 pluma Agonistas del GLP-1: posible terapia frente al COVID persistente en pacientes con diabetes GLP-1 Medications for Weight Loss

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Greater precision tends to produce more predictable pharmacologic effects, while variability can introduce uncertainty in both dosing and outcomes

The SELECT trial demonstrated a 20% reduction in major adverse cardiovascular events in 17,604 adults with preexisting cardiovascular disease, overweight or obesity, without diabetes [1] [2]

Meta-analysis of 34 trials showed that among GLP-1 receptor agonists, once-daily exenatide has the lowest risk of vomiting, while albiglutide had the highest risk for diarrhea

Table 1 summarizes these findings