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Patients with diabetes have been taking older versions of GLP-1 agonists for almost 20 years

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That was my biggest downfall. Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription 27,99 / 30 days cancel any time Subscribe to this journal Receive 52 print issues and online access 199,00 per year only 3,83 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout Nature 638 , 308-310 (2025) doi: References Jastreboff, A

Conclusion This novel study in youth with type 2 diabetes demonstrated that short-term metformin improved postprandial blood glucose levels and was associated with modest increases in incretin concentrations in the absence of changes in rates of glucose production and gluconeogenesis

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