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How to Maximise Safety While on Wegovy If you and your doctor decide that the benefits outweigh the risks, there are steps you can take to ensure the treatment remains as safe as possible

In major clinical trials, such as the landmark STEP 1 trial published in the New England Journal of Medicine , a once-weekly injection of semaglutide 2.4 mg resulted in an average body weight reduction of roughly 14.9% over 68 weeks
Direct answer: Clear medical need strengthens approval because insurers want objective reasons for treatment

Seek urgent medical attention immediately for chest pain, vomiting blood, black tarry stools, or sudden severe abdominal pain, which may indicate a serious condition such as pancreatitis or gastrointestinal bleeding

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