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Byetta is expected to lose patent protection soon, and a generic injectable exenatide has been filed with the FDA [174]

Weight loss medications are transforming the way we approach obesity and weight-related health conditions

Other data pose the gut-brain GLP-1R axis in a concept of brain-immune networks for suppression of peripheral inflammation [203]

Misfolded proinsulin in the endoplasmic reticulum during development of beta cell failure in diabetes

In parallel with the STEP studies, the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) studies were also conducted to evaluate cardiovascular benefits in individuals with obesity or overweight