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In terms of addressing fatigue syndrome, Garvey said most people respond well to lowering the medication dose and a few will require at least temporary discontinuation

Discuss your options with a healthcare provider to determine the best approach for your weight management strategy

A search of the trial literature and registries finds retatrutide studied in obesity, in type 2 diabetes, in MASLD, in knee osteoarthritis with obesity, and in cardiovascular-disease populations but not in a cohort defined by PCOS, and not with PCOS-specific reproductive or androgen endpoints
It's a real effect, but I'd keep it honest, he explains

PlexusDx providers review your endoscopy results and current medications to determine if starting semaglutide now is safe, or if waiting 24 weeks for inflammation to improve is wiser
